On March 18th, 1781, Lucretia Hart Clay, the wife of Henry Clay, was born in Hagerstown, Maryland. Lucretia and Henry married on April 11th, 1799, at the Hart residence in Lexington, and had eleven children: Henrietta, Theodore, Thomas, Susan, Anne, Lucretia, Henry, Jr., Eliza, Laura, James Brown, and John. However, by 1835, all six daughters had died of varying causes, such as whooping cough, yellow fever, and complications from childbirth. Henry Clay, Jr. was killed at the Battle of Buena Vista during the Mexican-American War. Lucretia Hart Clay managed the Ashland estate for 50 years, before passing away in 1864 at the age of 83. She is now interred with her husband in the vault of his monument at the Lexington Cemetery.